BCL2L10 Protein (His tag)

Produktnummer ABIN1098488

Produktdetails

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses BCL2L10 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Bcl-2-like protein 10, BCL-B, Boo, Diva

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 20% glycerol, 1 MM DTT

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Andere Bezeichnung: BCL2L10 (BCL2L10 Produkte)

Synonyme: BCL-B Protein, Boo Protein, Diva Protein, AA420380 Protein, AU023065 Protein, C85687 Protein, NR-13 Protein, mcl1l Protein, nr13 Protein, sb:cb78 Protein, BCL2 like 10 Protein, Bcl2-like 10 Protein, BCL2-like 10 (apoptosis facilitator) Protein, BCL2L10 Protein, Bcl2l10 Protein, bcl2l10 Protein

Hintergrund: BCL2L10 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL2L10 contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this protein has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. Recombinant human BCL2L10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 21.8 kDa (195aa), confirmed by MALDI-TOF

NCBI Accession: NP_065129

Pathways: Positive Regulation of Endopeptidase Activity