Smooth Muscle Actin Protein (His tag)

Produktnummer ABIN1098398

Produktdetails

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Smooth Muscle Actin Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Actin, aortic smooth muscle, AAT6, ACTSA, MYMY5

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Andere Bezeichnung: ACTA2 (ACTA2 Produkte)

Synonyme: AAT6 Protein, ACTSA Protein, MYMY5 Protein, GAMMA-ACTIN Protein, ACT Protein, ACTA3 Protein, ACTE Protein, ACTL3 Protein, ACTSG Protein, Act-4 Protein, Act4 Protein, SMGA Protein, 0610041G09Rik Protein, Actvs Protein, SMalphaA Protein, a-SMA Protein, alphaSMA Protein, wu:fb63d03 Protein, ASMA Protein, SMactin Protein, a-sma Protein, aat6 Protein, actsa Protein, mymy5 Protein, sm-actin Protein, ACTA2 Protein, actc1 Protein, ACT-4 Protein, asma Protein, ACTGE Protein, actin, alpha 2, smooth muscle, aorta Protein, actin, gamma 2, smooth muscle, enteric Protein, actin, alpha 2, smooth muscle, aorta L homeolog Protein, ACTA2 Protein, ACTG2 Protein, Actg2 Protein, Acta2 Protein, acta2 Protein, acta2.L Protein

Hintergrund: ACTA2 belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. Recombinant human ACTA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 44.4 kDa (400aa), confirmed by MALDI-TOF

NCBI Accession: NP_001604

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development