ACADSB Protein (His tag)

Produktnummer ABIN1098335

Produktdetails

Target: ACADSB (Acyl-CoA Dehydrogenase, Short/branched Chain (ACADSB))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ACADSB Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial, 2-MEBCAD, ACAD7, SBCAD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol,1 MM DTT

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: ACADSB (Acyl-CoA Dehydrogenase, Short/branched Chain (ACADSB))

Andere Bezeichnung: ACADSB (ACADSB Produkte)

Synonyme: 2-mebcad Protein, acad7 Protein, sbcad Protein, DDBDRAFT_0185291 Protein, DDBDRAFT_0237707 Protein, DDB_0185291 Protein, DDB_0237707 Protein, 2-MEBCAD Protein, ACAD7 Protein, SBCAD Protein, 1300003O09Rik Protein, BB066609 Protein, acyl-CoA dehydrogenase, short/branched chain Protein, acyl-CoA dehydrogenase short/branched chain Protein, acyl-coenzyme A dehydrogenase, short/branched chain Protein, acyl-CoA dehydrogenase Protein, acyl-CoA dehydrogenase, short/branched chain L homeolog Protein, acyl-Coenzyme A dehydrogenase, short/branched chain Protein, ACADSB Protein, acadsb Protein, sce1166 Protein, acadsb.L Protein, Acadsb Protein

Hintergrund: Short/branched chain specific acyl-CoA dehydrogenase(ACADSB), is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. ACADSB catalyzes the degradation of L-isoleucine and has the highest affinity for (s)-2-methylbutyryl-CoA, isobutyryl-CoA and 2-methylhexanoyl-CoA as substrates. Defects in ACADSB are the cause of short/branched-chain acyl-CoA dehydrogenase deficiency (SBCADD), an autosomal recessive disorder characterized by an increase of 2-methylbutyrylglycine and 2-methylbutyrylcarnitine in blood and urine. Recombinant human ACADSB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 46.4 kDa (424aa)

NCBI Accession: NP_001600

Pathways: Monocarboxylic Acid Catabolic Process