TCEAL7 Protein (His tag)

Produktnummer ABIN1098326

Produktdetails

Target: TCEAL7 (Transcription Elongation Factor A (SII)-Like 7 (TCEAL7))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses TCEAL7 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 80 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Transcription elongation factor A (SII)-like 7, MPMGp800C04260Q003

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.2 M NaCl, 2 mM DTT

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: TCEAL7 (Transcription Elongation Factor A (SII)-Like 7 (TCEAL7))

Andere Bezeichnung: TCEAL7 (TCEAL7 Produkte)

Synonyme: MPMGp800C04260Q003 Protein, 1110018P05Rik Protein, transcription elongation factor A like 7 Protein, transcription elongation factor A (SII)-like 7 Protein, TCEAL7 Protein, Tceal7 Protein

Hintergrund: TCEAL7 plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. It associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. This protein regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres) and telomerase-positive cell lines. Recombinant human TCEAL7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 14.8kDa(124aa) confirmed by MALDI-TOF

NCBI Accession: NP_689491