SNF8 Protein (His tag)

Produktnummer ABIN1098312

Produktdetails

Target: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SNF8 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Vacuolar-sorting protein SNF8, Dot3, EAP30, VPS22

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer, pH 8.0, 50% glycerol, 2 mM DTT, 200 mM NaCl

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Andere Bezeichnung: SNF8 (SNF8 Produkte)

Synonyme: d11moh34 Protein, vps22 Protein, Dot3 Protein, EAP30 Protein, VPS22 Protein, D11moh34 Protein, RGD1310144 Protein, D11Moh34 Protein, D11MOH34 Protein, zgc:101578 Protein, SNF8, ESCRT-II complex subunit Protein, eap30 subunit of ell complex, putative Protein, EAP30 subunit of ELL complex Protein, SNF8, ESCRT-II complex subunit S homeolog Protein, SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) Protein, snf8 Protein, TA17290 Protein, TVAG_107410 Protein, Bm1_05145 Protein, SNF8 Protein, Snf8 Protein, snf8.S Protein

Hintergrund: SNF 8, also known as EAP30 (ELL-associated protein of 30 kDa), is localizes to both the nucleus and the cytoplasm and is a member of the SNF8 family of vacuolar sorting proteins. This protein is subunit of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Recombinant human SNF8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 31.4kDa (282aa) confirmed by MALDI-TOF

NCBI Accession: NP_009172