CKMT1A Protein (His tag)

Produktnummer ABIN1098309

Produktdetails

Target: CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CKMT1A Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Creatine kinase U-type, mitochondrial, CKMT1, CKMT1B, UMTCK

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))

Andere Bezeichnung: CKMT1A (CKMT1A Produkte)

Synonyme: CKMT1 Protein, Mt-CK Protein, ScCKmit Protein, UbCKmit Protein, mi-CK Protein, Ckmt1 Protein, CKMT1B Protein, Mia-CK Protein, U-MtCK Protein, creatine kinase, mitochondrial 1A Protein, creatine kinase U-type, mitochondrial-like Protein, creatine kinase, mitochondrial 1, ubiquitous Protein, creatine kinase U-type, mitochondrial Protein, CKMT1A Protein, LOC100228000 Protein, Ckmt1 Protein, LOC100725326 Protein

Hintergrund: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Recombinant human CKMT1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 45 kDa (403aa) confirmed by MALDI-TOF

NCBI Accession: NP_001015001