NMRK1 Protein (His tag)

Produktnummer ABIN1098295

Produktdetails

Target: NMRK1 (Nicotinamide Riboside Kinase 1 (NMRK1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses NMRK1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: nicotinamide riboside kinase 1 isoform 1, bA235O14.2, NRK1, RP11-235O14.2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer, pH 8.0, 10% glycerol, 2 mM DTT, 200 mM NaCl

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: NMRK1 (Nicotinamide Riboside Kinase 1 (NMRK1))

Andere Bezeichnung: NRK1 (NMRK1 Produkte)

Synonyme: C9orf95 Protein, NRK1 Protein, bA235O14.2 Protein, AA408380 Protein, D630020N23Rik Protein, Nrk1 Protein, zgc:113113 Protein, nicotinamide riboside kinase 1 Protein, NMRK1 Protein, Nmrk1 Protein, nmrk1 Protein

Hintergrund: NRK1 belongs to the uridine kinase family. NAD+ is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADPribosyl groups used in various reactions, including those that retard aging in experimental systems. Nicotinic acid and nicotinamide were defined as the vitamin precursors of NAD+. This enzyme catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the antitumor drugs tiazofurin and 3-deazaguanosine. Recombinant human NRK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 25.6kDa (222aa), confirmed by MALDI-TOF

NCBI Accession: NP_060351