EIF4H Protein (His tag)

Produktnummer ABIN1098293

Produktdetails

Target: EIF4H (Eukaryotic Translation Initiation Factor 4H (EIF4H))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses EIF4H Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Eukaryotic translation initiation factor 4H, eIF-4H, WBSCR1, WSCR1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 50% glycerol, 2 mM DTT

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: EIF4H (Eukaryotic Translation Initiation Factor 4H (EIF4H))

Andere Bezeichnung: EIF4H (EIF4H Produkte)

Synonyme: wscr1 Protein, wbscr1 Protein, WBSCR1 Protein, Wbscr1 Protein, WSCR1 Protein, eIF-4H Protein, AU018978 Protein, D5Ertd355e Protein, E430026L18Rik Protein, Ef4h Protein, Wscr1 Protein, mKIAA0038 Protein, zgc:77282 Protein, eukaryotic translation initiation factor 4H Protein, eukaryotic translation initiation factor 4H L homeolog Protein, eukaryotic translation initiation factor 4h Protein, transaltion initiation factor Protein, Eukaryotic translation initiation factor 4H Protein, eif4h Protein, eif4h.L Protein, EIF4H Protein, Eif4h Protein, LOC733087 Protein, SJAG_03433 Protein, MGYG_07815 Protein, Tsp_06589 Protein, if4h Protein

Hintergrund: Eukaryotic translation initiation factor 4H, also known as EIF4H, is a 248 amino acid protein that localizes to the perinuclear region of the cytoplasm and is expressed as two isoforms, designated short and long. EIF4H induces the RNA-dependent ATP hydrolysis catalyzed by the initiation factors EIF4A and EIF4B. EIF4H was further shown to stimulate the initial rate and extent of EIF4A-mediated mRNA secondary structure unwinding. Defects in the gene encoding EIF4H are associated with Williams- Beuren syndrome (WBS), a rare developmental disorder characterized by cardiovascular and musculo-skeletal abnormalities. Recombinant human EIF4H protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 29.9 kDa (272aa), confirmed by MALDI-TOF

NCBI Accession: NP_071496

Pathways: SARS-CoV-2 Protein Interaktom