GNAI3 Protein (His tag)

Produktnummer ABIN1098248

Produktdetails

Target: GNAI3 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GNAI3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Guanine nucleotide-binding protein G(k) subunit alpha, 87U6

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 20% glycerol, 100 mM NaCl

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: GNAI3 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 3 (GNAI3))

Andere Bezeichnung: GNAI3 (GNAI3 Produkte)

Synonyme: AI158965 Protein, AW537698 Protein, Galphai3 Protein, Gnai-3 Protein, 87U6 Protein, ARCND1 Protein, GIP3A Protein, G protein subunit alpha i3 Protein, guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 Protein, guanine nucleotide binding protein (G protein), alpha inhibiting 3 Protein, G protein subunit alpha i3 S homeolog Protein, GNAI3 Protein, gnai3 Protein, Gnai3 Protein, gnai3.S Protein

Hintergrund: GNAI3 belongs to the G-alpha family and G (i/o/t/z) subfamily. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor-regulated K+ channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. This protein plays a role in cell division. GNAI3 has been shown to interact with RGS14, RIC8A, RGS18, S1PR1, RGS12, RGS16, RGS19, RGS10 and RGS5. Recombinant human GNAI3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 43.0kDa (377aa), confirmed by MALDI-TOF

NCBI Accession: NP_006487

Pathways: cAMP Metabolic Process, G-protein mediated Events