OTC Protein (His tag)

Produktnummer ABIN7279762

Produktdetails

Target: OTC (Ornithine Carbamoyltransferase (OTC))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses OTC Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: ornithine carbamoyltransferase, OCTD, OTCase

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM MES buffer (pH 6.0) containing 2 mM DTT, 10% glycerol, 100 mM NaCl

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: OTC (Ornithine Carbamoyltransferase (OTC))

Andere Bezeichnung: OTC (OTC Produkte)

Synonyme: OCTD Protein, 2810428A13Rik Protein, AA589422 Protein, AW457381 Protein, OCT Protein, Plxn2 Protein, mKIAA0463 Protein, F1B16.13 Protein, F1B16_13 Protein, ORNITHINE CARBAMOYLTRANSFERASE Protein, ornithine carbamoyltransferase Protein, BA4351 Protein, PSPTO4164 Protein, PLXN2 Protein, AI265390 Protein, Sf Protein, spf Protein, si:dkey-19h21.3 Protein, ornithine carbamoyltransferase Protein, plexin A2 Protein, ornithine carbamoyltransferase ArgF Protein, ornithine transcarbamylase Protein, OTC Protein, Plxna2 Protein, Otc Protein, argF Protein, argF-2 Protein, atpD-2 Protein, CNC04300 Protein, PLXNA2 Protein, otc Protein

Hintergrund: OTC, also called ornithine carbamoyltransferase, belongs to the ATCase/OTCase family. OTC plays a vital role in the urea cycle, catalyzing the second step in this pathway: the formation of L-citrulline from L-orthinine and carbamoyl phosphate. In humans, the urea cycle is an important pathway to detoxification of ammonia. Mutations in the gene encoding OTC are associated with the X-linked disorder OTCD (ornithine carbamoyltransferase deficiency). OTCD is a disorder of the urea cycle characterized by hyperammonemia. Recombinant human OTC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 38.9kDa (347aa), confirmed by MALDI-TOF

NCBI Accession: NP_000522