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IFI30 Protein (His tag)

IFI30 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN1098216
  • Target Alle IFI30 Proteine anzeigen
    IFI30 (Interferon, gamma-Inducible Protein 30 (IFI30))
    Protein-Typ
    Recombinant
    Spezies
    • 6
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 3
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses IFI30 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Aufreinigung
    purified by chromatography
    Reinheit
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product IFI30 Protein
  • Kommentare

    Synonyms: Gamma-interferon-inducible lysosomal thiol reductase, GILT, IFI-30, IP30

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol,1 MM DTT
    Lagerung
    4 °C
    Informationen zur Lagerung
    Avoid repeated freezing and thawing cycles.
  • Target
    IFI30 (Interferon, gamma-Inducible Protein 30 (IFI30))
    Andere Bezeichnung
    IFI30 (IFI30 Produkte)
    Synonyme
    GILT Protein, wu:fb12b04 Protein, zgc:101752 Protein, IP30 Protein, IFI-30 Protein, interferon, gamma-inducible protein 30 Protein, IFI30, lysosomal thiol reductase Protein, interferon gamma inducible protein 30 Protein, ifi30 Protein, IFI30 Protein, LOC100304719 Protein, Ifi30 Protein
    Hintergrund
    IFI30, also as known as gamma-interferon-inducible lysosomal thiol reductase, belongs to the GILT family. This protein is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing. This protein facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds. Also facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or cross-presentation. Recombinant human IFI30 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional column chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
    Molekulargewicht
    22.5 kDa (199aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_006323
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