CLIC2 Protein (AA 1-247) (His tag)
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- Target Alle CLIC2 Proteine anzeigen
- CLIC2 (Chloride Intracellular Channel 2 (CLIC2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-247
- Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses CLIC2 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human Chloride Intracellular Channel Protein 2/CLIC2 (N-6His)
- Sequenz
- MGSSHHHHHH SSGLVPRGSH MSGLRPGTQV DPEIELFVKA GSDGESIGNC PFCQRLFMIL WLKGVKFNVT TVDMTRKPEE LKDLAPGTNP PFLVYNKELK TDFIKIEEFL EQTLAPPRYP HLSPKYKESF DVGCNLFAKF SAYIKNTQKE ANKNFEKSLL KEFKRLDDYL NTPLLDEIDP DSAEEPPVSR RLFLDGDQLT LADCSLLPKL NIIKVAAKKY RDFDIPAEFS GVWRYLHNAY AREEFTHTCP EDKEIENTYA NVAKQKS
- Produktmerkmale
- Recombinant Human Chloride Intracellular Channel Protein 2/CLIC2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ser247) of Human CLIC2 fused with a His tag at the N-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CLIC2 Protein
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Chloride Intracellular Channel 2 (CLIC2) (AA 1-247) protein (His tag)
CLIC2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chloride Intracellular Channel 2 (CLIC2) (AA 1-247) protein (GST tag)CLIC2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Chloride Intracellular Channel 2 (CLIC2) protein (Myc-DYKDDDDK Tag)CLIC2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Rekonstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 20 % Glycerol, pH 8.0.
- Konservierungsmittel
- Dithiothreitol (DTT)
- Vorsichtsmaßnahmen
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Lagerung
- -80 °C
- Informationen zur Lagerung
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Haltbarkeit
- 6 months
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- Target
- CLIC2 (Chloride Intracellular Channel 2 (CLIC2))
- Andere Bezeichnung
- Chloride Intracellular Channel Protein 2/CLIC2 (CLIC2 Produkte)
- Synonyme
- zgc:92762 Protein, CLIC2 Protein, CLIC2b Protein, MRXS32 Protein, XAP121 Protein, chloride intracellular channel 2 Protein, clic2 Protein, CLIC2 Protein, Clic2 Protein
- Sub Type
- Fusionprotein
- Hintergrund
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Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells, it regulates cellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, channel activity depends on the pH. CLIC2 is involved in regulating membrane potential and organic solute transport. CLIC2 modulates the activity of RYR2 and inhibits Calcium influx. CLIC2 can be detected in the adult brain, liver, lung, heart, stomach, spleen and testis. It is expressed in fetal liver and adult skeletal muscle. CLIC2 is a potential candidate for one of many diseases linked to Xq28.
Alternative Names: Chloride Intracellular Channel Protein 2, XAP121, CLIC2 - Molekulargewicht
- 30.5 kDa
- UniProt
- O15247
- Pathways
- Negative Regulation of Transporter Activity
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