UROS Protein (AA 1-265) (His tag)

Produktnummer ABIN1097769

Produktdetails

Target: UROS (Uroporphyrinogen III Synthase (UROS))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-265

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses UROS Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Uroporphyrinogen-III Synthase/UROIIIS (C-6His)

Sequenz: MKVLLLKDAK EDDCGQDPYI RELGLYGLEA TLIPVLSFEF LSLPSFSEKL SHPEDYGGLI FTSPRAVEAA ELCLEQNNKT EVWERSLKEK WNAKSVYVVG NATASLVSKI GLDTEGETCG NAEKLAEYIC SRESSALPLL FPCGNLKREI LPKALKDKGI AMESITVYQT VAHPGIQGNL NSYYSQQGVP ASITFFSPSG LTYSLKHIQE LSGDNIDQIK FAAIGPTTAR ALAAQGLPVS CTAESPTPQA LATGIRKALQ PHGCCLEHHH HHH

Produktmerkmale: Recombinant Human Uroporphyrinogen-III Synthase/UROIIIS is produced by our E.coli expression system. The target protein is expressed with sequence (Met1-Cys265) of Human UROS fused with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 10 % Glycerol, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: UROS (Uroporphyrinogen III Synthase (UROS))

Andere Bezeichnung: UROIIIS (UROS Produkte)

Synonyme: wu:fd13d11 Protein, zgc:110240 Protein, UROIIIS Protein, Afu6g12800 Protein, UROS Protein, MGC85561 Protein, AI415298 Protein, Uros3 Protein, ARABIDOPSIS THALIANA UROPORPHYRINOGEN III SYNTHASE Protein, ATDUF3 Protein, ATUROS Protein, DOMAIN OF UNKNOWN FUNCTION 724 3 Protein, DUF3 Protein, T9J22.21 Protein, T9J22_21 Protein, UROPORPHYRINOGEN III SYNTHASE Protein, uroporphyrinogen III synthase Protein, uroporphyrinogen-III synthase (UroS) Protein, uroporphyrinogen-iii synthase Protein, uroporphyrinogen III synthase L homeolog Protein, uroporphyrinogen-III synthase family protein Protein, uros Protein, UROS Protein, AFUA_6G12800 Protein, UroS Protein, uros.L Protein, Uros Protein, HEMD Protein

Sub Type: Fusionprotein

Hintergrund: Uroporphyrinogen-III Synthase is an enzyme which belongs to the uroporphyrinogen-III synthase family. Uroporphyrinogen-III Synthase is ubiquitous and it is involved in Porphyrin metabolism. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as Methionine synthesis (Vitamin B12) or oxygen transport (Heme). Uroporphyrinogen-III Synthase can catalyze cyclization of the linear Tetrapyrrole, Hydroxymethylbilane, to the Macrocyclic Uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of Porphyrins. Defects in Uroporphyrinogen-III Synthase are the cause of Congenital Erythropoietic Porphyria (CEP).
Alternative Names: Uroporphyrinogen-III Synthase, UROIIIS, UROS, Hydroxymethylbilane Hydrolyase [Cyclizing], Uroporphyrinogen-III Cosynthase, UROS

Molekulargewicht: 29.7 kDa

UniProt: P10746