UROD Protein (AA 1-367) (His tag)

Produktnummer ABIN1097765

Produktdetails

Target: UROD (Uroporphyrinogen Decarboxylase (UROD))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-367

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses UROD Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Uroporphyrinogen Decarboxylase/UROD (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MEANGLGPQG FPELKNDTFL RAAWGEETDY TPVWCMRQAG RYLPEFRETR AAQDFFSTCR SPEACCELTL QPLRRFPLDA AIIFSDILVV PQALGMEVTM VPGKGPSFPE PLREEQDLER LRDPEVVASE LGYVFQAITL TRQRLAGRVP LIGFAGAPWT LMTYMVEGGG SSTMAQAKRW LYQRPQASHQ LLRILTDALV PYLVGQVVAG AQALQLFESH AGHLGPQLFN KFALPYIRDV AKQVKARLRE AGLAPVPMII FAKDGHFALE ELAQAGYEVV GLDWTVAPKK ARECVGKTVT LQVNLDPCAL YASEEEIGQL VKQMLDDFGP HRYIANLGHG LYPDMDPEHV GAFVDAVHKH SRLLRQN

Produktmerkmale: Recombinant Human Uroporphyrinogen Decarboxylase/UROD is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Asn367) of Human UROD fused with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 1 mM EDTA, pH 8.0.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: UROD (Uroporphyrinogen Decarboxylase (UROD))

Andere Bezeichnung: Uroporphyrinogen Decarboxylase/UROD (UROD Produkte)

Synonyme: UROD Protein, pct Protein, wu:fc43e09 Protein, PCT Protein, UPD Protein, AI323803 Protein, Uro-d Protein, porphyrinogen carboxy-lyase Protein, uroporphyrinogen decarboxylase Protein, Uroporphyrinogen decarboxylase UroD Protein, Uroporphyrinogen decarboxylase Protein, UROD Protein, urod Protein, hemE Protein, uroD Protein, Cpin_6502 Protein, Rmar_1187 Protein, LOC5568261 Protein, Mrub_1403 Protein, Arnit_2230 Protein, Ndas_2830 Protein, Mesil_2989 Protein, Trad_0222 Protein, Weevi_0432 Protein, Hipma_1229 Protein, Fluta_0529 Protein, Marky_1143 Protein, Halhy_5610 Protein, Mesop_0899 Protein, Ccan_20670 Protein, Urod Protein

Sub Type: Fusionprotein

Hintergrund: Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. UROD is a homodimeric enzyme that catalyzes the fifth step in heme biosynthesis: the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield coproporphyrinogen III. Defects in UROD are the cause of familial porphyria cutanea tarda (FPCT) and hepatoerythropoietic porphyria (HEP).
Alternative Names: Uroporphyrinogen Decarboxylase, UPD, URO-D, UROD

Molekulargewicht: 43 kDa

UniProt: P06132