PRSS22 Protein (AA 33-317) (His tag)

Produktnummer ABIN1097712

Produktdetails

Target: PRSS22 (Protease, serine, 22 (PRSS22))

Protein-Typ: Recombinant

Proteineigenschaft: AA 33-317

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses PRSS22 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Tryptase epsilon/Brain-Specific Serine Protease 4/BSSP-4 (C-6His)

Sequenz: ARIPVPPACG KPQQLNRVVG GEDSTDSEWP WIVSIQKNGT HHCAGSLLTS RWVITAAHCF KDNLNKPYLF SVLLGAWQLG NPGSRSQKVG VAWVEPHPVY SWKEGACADI ALVRLERSIQ FSERVLPICL PDASIHLPPN THCWISGWGS IQDGVPLPHP QTLQKLKVPI IDSEVCSHLY WRGAGQGPIT EDMLCAGYLE GERDACLGDS GGPLMCQVDG AWLLAGIISW GEGCAERNRP GVYISLSAHR SWVEKIVQGV QLRGRAQGGG ALRAPSQGSG AAARSHHHHH H

Produktmerkmale: Recombinant Human Brain-Specific Serine Protease 4/BSSP-4 produced by transfected human cells is a secreted protein with sequence(Ala33-Ser317) of Human BSSP-4 Tryptase fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, 10 % Glycerol, pH 4.5.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: PRSS22 (Protease, serine, 22 (PRSS22))

Andere Bezeichnung: tryptase-epsilon (PRSS22 Produkte)

Synonyme: BSSP-4 Protein, hBSSP-4 Protein, 4733401N09Rik Protein, SP001LA Protein, protease, serine, 22 Protein, protease, serine 22 Protein, Prss22 Protein, PRSS22 Protein

Sub Type: Fusionprotein

Hintergrund: Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after arginine and lysine residues. However, BSSP-4 is less susceptible to inhibition by common trypsin inhibitors such as aprotinin, alpha1-antitrypsin and secretory leukocyte protease inhibitor. BSSP-4 efficiently converts pro-urokinase- type plasminogen activator to its mature, active form.
Alternative Names: Brain-Specific Serine Protease 4, BSSP-4, Serine Protease 22, Serine Protease 26, Tryptase Epsilon, PRSS22, BSSP4, PRSS26

Molekulargewicht: 31.56 kDa

UniProt: Q9GZN4