LRP12 Protein (AA 28-488) (His tag)

Produktnummer ABIN1097586

Produktdetails

Target: LRP12 (Low Density Lipoprotein Receptor-Related Protein 12 (LRP12))

Protein-Typ: Recombinant

Proteineigenschaft: AA 28-488

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses LRP12 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Low-Density Lipoprotein Receptor Related Protein 12/LRP12 (C-6His)

Sequenz: NGALAEHSEN VHISGVSTAC GETPEQIRAP SGIITSPGWP SEYPAKINCS WFIRANPGEI ITISFQDFDI QGSRRCNLDW LTIETYKNIE SYRACGSTIP PPYISSQDHI WIRFHSDDNI SRKGFRLAYF SGKSEEPNCA CDQFRCGNGK CIPEAWKCNN MDECGDSSDE EICAKEANPP TAAAFQPCAY NQFQCLSRFT KVYTCLPESL KCDGNIDCLD LGDEIDCDVP TCGQWLKYFY GTFNSPNYPD FYPPGSNCTW LIDTGDHRKV ILRFTDFKLD GTGYGDYVKI YDGLEENPHK LLRVLTAFDS HAPLTVVSSS GQIRVHFCAD KVNAARGFNA TYQVDGFCLP WEIPCGGNWG CYTEQQRCDG YWHCPNGRDE TNCTMCQKEE FPCSRNGVCY PRSDRCNYQN HCPNGSDEKN CFFCQPGNFH CKNNRCVFES WVCDSQDDCG DGSDEENCPV IVDHHHHHH

Produktmerkmale:

Recombinant Human Low-Density Lipoprotein Receptor Related Protein 12/LRP12 (C-6His)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: LRP12 (Low Density Lipoprotein Receptor-Related Protein 12 (LRP12))

Andere Bezeichnung: Low-Density Lipoprotein Receptor Related Protein 12 (LRP12 Produkte)

Synonyme: DKFZp459F2124 Protein, ST7 Protein, AI848829 Protein, C820005L12Rik Protein, LRP-12 Protein, LDL receptor related protein 12 Protein, low density lipoprotein-related protein 12 Protein, LRP12 Protein, lrp12 Protein, Lrp12 Protein

Hintergrund: Recombinant Human Low-Density Lipoprotein Receptor-Related Protein 12/LRP12 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Glu33-Arg492) of Human ST7 fused with a polyhistidine tag at the C-terminus.
Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as a tumor suppressor.

Molekulargewicht: 52.48 kDa

UniProt: Q9Y561