SERPINA4 Protein (AA 21-427) (His tag)

Produktnummer ABIN1097508

Produktdetails

Target: SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-427

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses SERPINA4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Serpin A4/Kallistatin (C-6His)

Sequenz: QLHVEHDGES CSNSSHQQIL ETGEGSPSLK IAPANADFAF RFYYLIASET PGKNIFFSPL SISAAYAMLS LGACSHSRSQ ILEGLGFNLT ELSESDVHRG FQHLLHTLNL PGHGLETRVG SALFLSHNLK FLAKFLNDTM AVYEAKLFHT NFYDTVGTIQ LINDHVKKET RGKIVDLVSE LKKDVLMVLV NYIYFKALWE KPFISSRTTP KDFYVDENTT VRVPMMLQDQ EHHWYLHDRY LPCSVLRMDY KGDATVFFIL PNQGKMREIE EVLTPEMLMR WNNLLRKRNF YKKLELHLPK FSISGSYVLD QILPRLGFTD LFSKWADLSG ITKQQKLEAS KSFHKATLDV DEAGTEAAAA TSFAIKFFSA QTNRHILRFN RPFLVVIFST STQSVLFLGK VVDPTKPHHH HHH

Produktmerkmale: Recombinant Human Serpin A4 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln21-Pro427) of Human SERPINA4 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM TrisHCl, 150 mM NaCl, 10 mM NaCl, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))

Andere Bezeichnung: Serpin-A4 (SERPINA4 Produkte)

Synonyme: KLKR Protein, Klk6 Protein, hK1 Protein, KAL Protein, KLST Protein, KST Protein, PI-4 Protein, PI4 Protein, kallistatin Protein, SERPINA4 Protein, DKFZp469E1737 Protein, KALps Protein, Klst Protein, kallikrein 1 Protein, serpin family A member 4 Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 Protein, serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 Protein, KLK1 Protein, SERPINA4 Protein, Serpina4 Protein, SPIA4 Protein, Serpina4-ps1 Protein

Sub Type: Fusionprotein

Hintergrund: Serpin Peptidase Inhibitor, Clade A (alpha-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and secreted in plasma. Serpin A4 is a regulator of vascular homeostasis capable of controlling a wide spectrum of biological actions in the cardiovascular and renal systems. It can inhibit intracellular reactive oxygen species formation in cultured cardiac and renal cells. In addition, Serpin A4 has anti-inflammatory effect. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.
Alternative Names: Kallistatin, Kallikrein Inhibitor, Peptidase Inhibitor 4, PI-4, Serpin A4, SERPINA4, KST, PI4

Molekulargewicht: 47.1 kDa

UniProt: P29622