SCO1 Protein (AA 132-300) (GST tag)

Produktnummer ABIN1097478

Produktdetails

Target: SCO1 (SCO1 Cytochrome C Oxidase Assembly Protein (SCO1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 132-300

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SCO1 Protein ist gelabelt mit GST tag.

Verwendungszweck: Recombinant Human Protein SCO1 Homolog Mitochondrial SCO1/SCOD1 (N-GST)

Sequenz: GSPEFHMGKP LLGGPFSLTT HTGERKTDKD YLGQWLLIYF GFTHCPDVCP EELEKMIQVV DEIDSITTLP DLTPLFISID PERDTKEAIA NYVKEFSPKL VGLTGTREEV DQVARAYRVY YSPGPKDEDE DYIVDHTIIM YLIGPDGEFL DYFGQNKRKG EIAASIATHM RPYRKKS

Produktmerkmale: Recombinant Human Protein SCO1 Homolog, Mitochondrial/SCO1 is produced by our E. coli expression system. The target protein is expressed with sequence (Gly132-Ser300) of Human SCO1.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM PB, 1 mM DTT, pH 7.2.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: SCO1 (SCO1 Cytochrome C Oxidase Assembly Protein (SCO1))

Andere Bezeichnung: Protein SCO1 Homolog Mitochondrial (SCO1 Produkte)

Synonyme: SCOD1 Protein, 2610001C07Rik Protein, D11Bwg1310e Protein, SCO1 Protein, RGD1559538 Protein, SCO1, cytochrome c oxidase assembly protein Protein, SCO1 cytochrome c oxidase assembly protein Protein, SCO1 Protein, Sco1 Protein, sco1 Protein

Hintergrund: Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by high rates of Oxidative Phosphorylation (OxPhos). SCO1 is thought to play a important role in cellular copper homeostasis, mitochondrial redox signaling and insertion of copper into the active site of COX. The defects of SCO1 can result in Mitochondrial Complex IV Deficiency (MT-C4D). A disorder of the mitochondrial respiratory chain has heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs.
Alternative Names: Protein SCO1 Homolog Mitochondrial, SCO1, SCOD1

Molekulargewicht: 20.14 kDa

UniProt: O75880

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity