Neuroligin 1 Protein (NLGN1) (AA 46-694) (His tag)

Produktnummer ABIN1097221

Produktdetails

Target: Neuroligin 1 (NLGN1)

Protein-Typ: Recombinant

Proteineigenschaft: AA 46-694

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Neuroligin 1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Neuroligin-1/NLGN1 (C-6His)

Sequenz: QKLDDVDPLV ATNFGKIRGI KKELNNEILG PVIQFLGVPY AAPPTGERRF QPPEPPSPWS DIRNATQFAP VCPQNIIDGR LPEVMLPVWF TNNLDVVSSY VQDQSEDCLY LNIYVPTEDD IRDSGGPKPV MVYIHGGSYM EGTGNLYDGS VLASYGNVIV ITVNYRLGVL GFLSTGDQAA KGNYGLLDLI QALRWTSENI GFFGGDPLRI TVFGSGAGGS CVNLLTLSHY SEGNRWSNST KGLFQRAIAQ SGTALSSWAV SFQPAKYARM LATKVGCNVS DTVELVECLQ KKPYKELVDQ DIQPARYHIA FGPVIDGDVI PDDPQILMEQ GEFLNYDIML GVNQGEGLKF VENIVDSDDG ISASDFDFAV SNFVDNLYGY PEGKDVLRET IKFMYTDWAD RHNPETRRKT LLALFTDHQW VAPAVATADL HSNFGSPTYF YAFYHHCQTD QVPAWADAAH GDEVPYVLGI PMIGPTELFP CNFSKNDVML SAVVMTYWTN FAKTGDPNQP VPQDTKFIHT KPNRFEEVAW TRYSQKDQLY LHIGLKPRVK EHYRANKVNL WLELVPHLHN LNDISQYTST TTKVPSTDIT FRPTRKNSVP VTSAFPTAKQ DDPKQQPSPF SVDQRDYSTE LVDHHHHHH

Produktmerkmale: Recombinant Human Neuroligin 1/NLGN1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Q46-S694) of Human NLGN1 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: Neuroligin 1 (NLGN1)

Andere Bezeichnung: Neuroligin-1 (NLGN1 Produkte)

Synonyme: NLGN1 Protein, Nlgn1 Protein, GB18720 Protein, nlgn1 Protein, NL1 Protein, 6330415N05Rik Protein, BB179718 Protein, mKIAA1070 Protein, neuroligin-1 Protein, neuroligin 1 Protein, NLGN1 Protein, LOC659779 Protein, LOC724358 Protein, nlgn1 Protein, Nlgn1 Protein

Sub Type: Fusionprotein

Hintergrund: Neuroligin-1 is a single-pass type I transmembrane protein which belongs to the type-B Carboxylesterase/Lipase family. Neuroligins are cell-adhesion molecules located at the postsynaptic side of the synapse. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses. Neurexins and Neuroligins are cell adhesion molecules present in excitatory and inhibitory synapses, and they are required for correct neuron network function. These proteins are found at the presynaptic and postsynaptic membranes. Neuroligin-1 is a neuronal cell surface protein which is thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. It seems to play role in formation or maintenance of synaptic junctions. It triggers the de novo formation of presynaptic structures and may be involved in specification of excitatory synapses.
Synonyms: Neuroligin-1, NLGN1, KIAA1070

Molekulargewicht: 71.5 kDa

UniProt: Q8N2Q7

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis