DCXR Protein (AA 1-244) (His tag)

Produktnummer ABIN1097044

Produktdetails

Target: DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-244

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses DCXR Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human L-Xylulose Reductase/DCXR (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MELFLAGRRV LVTGAGKGIG RGTVQALHAT GARVVAVSRT QADLDSLVRE CPGIEPVCVD LGDWEATERA LGSVGPVDLL VNNAAVALLQ PFLEVTKEAF DRSFEVNLRA VIQVSQIVAR GLIARGVPGA IVNVSSQCSQ RAVTNHSVYC STKGALDMLT KVMALELGPH KIRVNAVNPT VVMTSMGQAT WSDPHKAKTM LNRIPLGKFA EVEHVVNAIL FLLSDRSGMT TGSTLPVEGG FWAC

Produktmerkmale: Recombinant Human L-Xylulose Reductase/DCXR is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Cys244) of Human DCXR fused with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 50 mM Tris, 150 mM NaCl, 1 mM DTT, 30 % Glycerol, 1 mM DTT, pH 8.0.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))

Andere Bezeichnung: L-Xylulose Reductase/DCXR (DCXR Produkte)

Synonyme: DCR Protein, HCR2 Protein, HCRII Protein, KIDCR Protein, P34H Protein, SDR20C1 Protein, XR Protein, dcxr Protein, DCXR Protein, DER Protein, 0610038K04Rik Protein, 1810027P18Rik Protein, glb Protein, wu:fa12f09 Protein, zgc:111977 Protein, GLB Protein, dicarbonyl and L-xylulose reductase Protein, dicarbonyl/L-xylulose reductase Protein, dicarbonyl L-xylulose reductase Protein, L-xylulose reductase Protein, L-xylulose reductase, putative Protein, dicarbonyl/L-xylulose reductase L homeolog Protein, DCXR Protein, dcxr Protein, Dcxr Protein, CNL05930 Protein, NCU09041 Protein, AOR_1_494194 Protein, VDBG_02657 Protein, CGB_D1070C Protein, dcxr.L Protein

Sub Type: Fusionprotein

Hintergrund: L-Xylulose Reductase is an enzyme that belongs to the Short-Chain Dehydrogenases/Reductases (SDR) family. L-Xylulose Reductase is responsible for the metabolism of Xylulose, converting it into Xylitol. L-Xylulose Reductase catalyzes the NADPH-dependent reduction of several Pentoses, Tetroses, Trioses, alpha-Dicarbonyl compounds and L-Xylulose. L-Xylulose Reductase participates in the Uronate Cycle of Glucose metabolism. It may play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing Xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
Alternative Names: L-Xylulose Reductase, XR, Carbonyl Reductase II, Dicarbonyl/L-Xylulose Reductase, Kidney Dicarbonyl Reductase, kiDCR, Sperm Surface Protein P34H, DCXR

Molekulargewicht: 28.1 kDa

UniProt: Q7Z4W1

Pathways: Glycosaminoglycan Metabolic Process, Monocarboxylic Acid Catabolic Process