Elastase 4 Protein (AA 17-268) (His tag)

Produktnummer ABIN1691229

Produktdetails

Target: Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))

Protein-Typ: Recombinant

Proteineigenschaft: AA 17-268

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Elastase 4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Chymotrypsin-C/CTRC (C-6His)

Sequenz: CGVPSFPPNL SARVVGGEDA RPHSWPWQIS LQYLKNDTWR HTCGGTLIAS NFVLTAAHCI SNTRTYRVAV GKNNLEVEDE EGSLFVGVDT IHVHKRWNAL LLRNDIALIK LAEHVELSDT IQVACLPEKD SLLPKDYPCY VTGWGRLWTN GPIADKLQQG LQPVVDHATC SRIDWWGFRV KKTMVCAGGD GVISACNGDS GGPLNCQLEN GSWEVFGIVS FGSRRGCNTR KKPVVYTRVS AYIDWINEKM QLVDHHHHHH

Produktmerkmale: Recombinant Human Chymotrypsin-C/CTRC produced by transfected human cells is a secreted protein with sequence (Cys17-Leu268) of Human CTRC fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))

Andere Bezeichnung: chymotrypsin-c (CTRC Produkte)

Synonyme: CLCR Protein, ELA4 Protein, 1810044E12Rik Protein, bPTLP Protein, chymotrypsin C Protein, chymotrypsin-C Protein, chymotrypsin C (caldecrin) Protein, CTRC Protein, LOC478220 Protein, Ctrc Protein

Sub Type: Fusionprotein

Hintergrund: Chymotrypsin C (CTRC) is a member of the peptidase S1 family. CTRC is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. CTRC has broad substrate specificity, but prefers to cleave on the carboxyl side of hydrophobic residues. CTRC is expressed primarily in the pancreas, and is secreted into the digestive tract. CTRC plays a protective role in the pancreas by mitigating premature trypsinogen activation through degradation. It has been proposed that CTRC is a key regulator of digestive zymogen activation and is a physiological coactivator of digestive carboxypeptidases proCPA1 and proCPA2. The mutation of CTRC gene encodes the digestive enzyme CTRC contribute to the development of pancreatitis.
Alternative Names: Chymotrypsin-C, Caldecrin, CTRC, CLCR

Molekulargewicht: 29 kDa

UniProt: Q99895