CD177 Protein (AA 22-407) (His tag)

Produktnummer ABIN1096299

Produktdetails

Target: CD177 (CD177 Molecule (CD177))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-407

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses CD177 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PRV1/CD177(C-6His)

Sequenz: LLCQFGTVQH VWKVSDLPRQ WTPKNTSCDS GLGCQDTLML IESGPQVSLV LSKGCTEAKD QEPRVTEHRM GPGLSLISYT FVCRQEDFCN NLVNSLPLWA PQPPADPGSL RCPVCLSMEG CLEGTTEEIC PKGTTHCYDG LLRLRGGGIF SNLRVQGCMP QPGCNLLNGT QEIGPVGMTE NCNRKDFLTC HRGTTIMTHG NLAQEPTDWT TSNTEMCEVG QVCQETLLLL DVGLTSTLVG TKGCSTVGAQ NSQKTTIHSA PPGVLVASYT HFCSSDLCNS ASSSSVLLNS LPPQAAPVPG DRQCPTCVQP LGTCSSGSPR MTCPRGTTHC YDGYIHLSGG GLSTKMSIQG CVAQPSSFLL NHTRQIGIFS AREKRDVQPP ASQHEGVDHH HHHH

Produktmerkmale: Recombinant Human CD177 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Leu22-Gly407) of Human CD177 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: CD177 (CD177 Molecule (CD177))

Andere Bezeichnung: cd177 (CD177 Produkte)

Synonyme: HNA-2a Protein, HNA2A Protein, NB1 Protein, NB1 GP Protein, PRV-1 Protein, PRV1 Protein, RGD1562941 Protein, CD177 Protein, MGC157159 Protein, 1190003K14Rik Protein, Pdp3 Protein, CD177 molecule Protein, CD177 antigen Protein, CD177 Protein, Cd177 Protein

Sub Type: Fusionprotein

Hintergrund: CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors,and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. PRV1 may also be expressed by Erythroblasts, B cells, and Monocytes. NB1, a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia. It is reported that CD177 functions as a novel heterophilic binding partner that engages PECAM-1 in membrane-proximal IgD6.
Alternative Names: CD177 Antigen, Human Neutrophil Alloantigen 2a, HNA-2a, NB1 Glycoprotein, NB1 GP, Polycythemia Rubra Vera Protein 1, PRV-1, CD177, NB1, PRV1

Molekulargewicht: 42.33 kDa

UniProt: Q8N6Q3