C1QTNF1 Protein (AA 26-281) (His tag)

Produktnummer ABIN1096167

Produktdetails

Target: C1QTNF1 (C1q and Tumor Necrosis Factor Related Protein 1 (C1QTNF1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 26-281

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses C1QTNF1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human C1qTNF1/CTRP1 (C-6His)

Sequenz: RVPHVQGEQQ EWEGTEELPS PPDHAERAEE QHEKYRPSQD QGLPASRCLR CCDPGTSMYP ATAVPQINIT ILKGEKGDRG DRGLQGKYGK TGSAGARGHT GPKGQKGSMG APGERCKSHY AAFSVGRKKP MHSNHYYQTV IFDTEFVNLY DHFNMFTGKF YCYVPGLYFF SLNVHTWNQK ETYLHIMKNE EEVVILFAQV GDRSIMQSQS LMLELREQDQ VWVRLYKGER ENAIFSEELD TYITFSGYLV KHATEPVDHH HHHH

Produktmerkmale: Recombinant Human Complement C1q Tumor Necrosis Factor-Related Protein 1/C1QTNF1 produced by transfected human cells is a secreted protein with sequence (Arg26-Pro281) of Human C1QTNF1 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: C1QTNF1 (C1q and Tumor Necrosis Factor Related Protein 1 (C1QTNF1))

Andere Bezeichnung: c1qtnf1 (C1QTNF1 Produkte)

Synonyme: C1QTNF1 Protein, CTRP1 Protein, GIP Protein, ZSIG37 Protein, 1600017K21Rik Protein, Zsig37 Protein, Ctrp1 Protein, zgc:113062 Protein, C1q and tumor necrosis factor related protein 1 Protein, C1q and TNF related 1 Protein, C1QTNF1 Protein, c1qtnf1 Protein, C1qtnf1 Protein

Sub Type: Fusionprotein

Hintergrund: C1QTNF1 is a secreted protein，contains 1 C1q domain and 1 collagen-like domain. C1qTNF proteins constitute a highly conserved family of Acrp30/Adiponectin paralogs that share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain and a C-terminal globular domain. C1qTNF proteins are predicted to have trimeric structures that assemble into hexameric and higher order molecular forms. C1QTNF1 is a novel adipokine, providing a significant framework to further address the physiological functions and mechanisms of the action of this family of secreted glycoproteins in normal and disease states. C1QTNF1 increases the production of aldosterone. C1QTNF1 is vastly expressed in obese subjects as well as up-regulated in hypertensive patients, C1QTNF1 is identified molecular link between obesity and hypertension. C1QTNF1 expression may be associated with a low-grade chronic inflammation status in adipose tissues.
Alternative Names: Complement C1q Tumor Necrosis Factor-Related Protein 1, G Protein-Coupled Receptor-Interacting Protein, GIP, C1QTNF1, CTRP1

Molekulargewicht: 30.24 kDa

UniProt: Q9BXJ1