Asialoglycoprotein Receptor 1 Protein (ASGR1) (AA 62-291) (His tag)

Produktnummer ABIN1096056

Produktdetails

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Protein-Typ: Recombinant

Proteineigenschaft: AA 62-291

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Asialoglycoprotein Receptor 1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Asialoglycoprotein Receptor 1/ASGPR1 (C-6His)

Sequenz: QNSQLQEELR GLRETFSNFT ASTEAQVKGL STQGGNVGRK MKSLESQLEK QQKDLSEDHS SLLLHVKQFV SDLRSLSCQM AALQGNGSER TCCPVNWVEH ERSCYWFSRS GKAWADADNY CRLEDAHLVV VTSWEEQKFV QHHIGPVNTW MGLHDQNGPW KWVDGTDYET GFKNWRPEQP DDWYGHGLGG GEDCAHFTDD GRWNDDVCQR PYRWVCETEL DKASQEPPLL VDHHHHHH

Produktmerkmale: Recombinant Human Asialoglycoprotein Receptor 1/ASGPR1 produced by transfected human cells is a secreted protein with sequence (Gln62-Ile291) of Human ASGPR1 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Andere Bezeichnung: asgpr1 (ASGR1 Produkte)

Synonyme: ASGR1 Protein, ASGPR Protein, ASGPR1 Protein, CLEC4H1 Protein, HL-1 Protein, Asgr Protein, Asgr-1 Protein, ASGR Protein, RATRHL1 Protein, RHL1 Protein, asialoglycoprotein receptor 1 Protein, LOC721786 Protein, ASGR1 Protein, LOC489461 Protein, Asgr1 Protein, LOC101116157 Protein

Sub Type: Fusionprotein

Hintergrund: Asialoglycoprotein Receptor 1 (ASGPR1) is an endocytic recycling receptor, belongs to the long-form subfamily of the C-type/Ca2+-dependent lectin family. ASGPR consists of two noncovalently-linked subnits, ASGPR1 and ASGPR2. ASGPR1 mediates the endocytosis of plasma glycoproteins, recognizes terminal galactose and N-acetylgalactosamine units. When the ligand binds to to ASGPR1, results in the complex is internalized and transported to a sorting organelle, then ASGPR1 and ligand can be disassociated, ASGPR1 returns to the cell membrane surface.
Alternative Names: Asialoglycoprotein Receptor 1, ASGP-R 1, ASGPR 1, C-Type Lectin Domain Family 4 Member H1, Hepatic Lectin H1, HL-1, ASGR1, CLEC4H1

Molekulargewicht: 27.43 kDa

UniProt: P07306

Pathways: Thyroid Hormone Synthesis