ICAM1 Protein (AA 28-480, partial) (GST tag)
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- Target Alle ICAM1 Proteine anzeigen
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 28-480, partial
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses ICAM1 Protein ist gelabelt mit GST tag.
- Applikation
- ELISA
- Sequenz
- QTSVSPSKVI LPRGGSVLVT CSTSCDQPKL LGIETPLPKK ELLLPGNNRK VYELSNVQED SQPMCYSNCP DGQSTAKTFL TVYWTPERVE LAPLPSWQPV GKNLTLRCQV EGGAPRANLT VVLLRGEKEL KREPAVGEPA EVTTTVLVRR DHHGANFSCR TELDLRPQGL ELFENTSAPY QLQTFVLPAT PPQLVSPRVL EVDTQGTVVC SLDGLFPVSE AQVHLALGDQ RLNPTVTYGN DSFSAKASVS VTAEDEGTQR LTCAVILGNQ SQETLQTVTI YSFPAPNVIL TKPEVSEGTE VTVKCEAHPR AKVTLNGVPA QPLGPRAQLL LKATPEDNGR SFSCSATLEV AGQLIHKNQT RELRVLYGPR LDERDCPGNW TWPENSQQTP MCQAWGNPLP ELKCLKDGTF PLPIGESVTV TRDLEGTYLC RARSTQGEVT RKVTVNVLSP RYE
- Produktmerkmale
- Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
- Reinheit
- 90 %
- Top Product
- Discover our top product ICAM1 Protein
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- Kommentare
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The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Konzentration
- 0.2-2 mg/mL
- Buffer
- Tris-based buffer, 50 % glycerol
- Handhabung
- Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
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cDNA cloning reveals that the major group rhinovirus receptor on HeLa cells is intercellular adhesion molecule 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 13, pp. 4907-11, (1989) (PubMed).
: "Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families." in: Cell, Vol. 52, Issue 6, pp. 925-33, (1988) (PubMed).
: "ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM." in: Nature, Vol. 331, Issue 6157, pp. 624-7, (1988) (PubMed).
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cDNA cloning reveals that the major group rhinovirus receptor on HeLa cells is intercellular adhesion molecule 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 13, pp. 4907-11, (1989) (PubMed).
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- Target
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- Andere Bezeichnung
- Intercellular adhesion molecule 1 protein (ICAM1 Produkte)
- Synonyme
- BB2 Protein, CD54 Protein, P3.58 Protein, Icam-1 Protein, Ly-47 Protein, MALA-2 Protein, ICAM Protein, ICAM-1 Protein, ICAM1 Protein, intercellular adhesion molecule 1 Protein, intercellular adhesion molecule-1 Protein, ICAM1 Protein, Icam1 Protein, ICAM-1 Protein
- Substanzklasse
- Viral Protein
- Hintergrund
- ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
- Molekulargewicht
- 76.9 kD
- UniProt
- P05362
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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