Insulin (INS) (AA 9-23) Peptid
INS
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- Target Alle Insulin (INS) Produkte
- Insulin (INS)
- Protein Region
- AA 9-23
- Sequenz
- One-letter code: SHLVEALYLV CGERG, Three-letter code: {Ser}{His}{Leu}{Val}{Glu}{Ala}{Leu}{Tyr}{Leu}{Val}{Cys}{Gly}{Glu}{Arg}{Gly
- Produktmerkmale
- Formula: C72H116N20O22S1
- Reinheit
- > 95 %
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Insulin (INS) peptide (Ovalbumin)
INS Reaktivität: Schwein Wirt: Synthetic Imm, SDS, WB
Insulin (INS) peptide (Ovalbumin)INS Reaktivität: Rind (Kuh) Wirt: Synthetic Imm, SDS, WB
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Lagerung
- -20 °C
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- Target
- Insulin (INS)
- Synonyme
- IDDM2 Peptide, ILPR Peptide, IRDN Peptide, MODY10 Peptide, ins1 Peptide, xins Peptide, ins1-a Peptide, Insulin Peptide, AA986540 Peptide, Ins-2 Peptide, InsII Peptide, Mody Peptide, Mody4 Peptide, proinsulin Peptide, zgc:109842 Peptide, igf2-A Peptide, ins Peptide, ins-a Peptide, ins-b Peptide, insulin Peptide, insulin precursor Peptide, insulin II Peptide, preproinsulin Peptide, insulin L homeolog Peptide, insulin S homeolog Peptide, INS Peptide, INS-IGF2 Peptide, ins Peptide, Ins Peptide, PIN Peptide, Ins2 Peptide, ins.L Peptide, ins.S Peptide
- Hintergrund
- This insulin B-chain peptide binds to a class II histocompatibility complex (MHC) allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic beta cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis.
- Molekulargewicht
- 1645.9
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