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Xylosyltransferase II (XYLT2) Peptid

XYLT2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN986277
  • Target Alle XYLT2 Produkte
    XYLT2 (Xylosyltransferase II (XYLT2))
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-XYLT2 antibody (Catalog #: ARP49703_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    XYLT2 (Xylosyltransferase II (XYLT2))
    Synonyme
    MGC89331 Peptide, PXYLT2 Peptide, XT-II Peptide, XT2 Peptide, xylT-II Peptide, xt-II Peptide, E030002B02Rik Peptide, xylt-II Peptide, xylosyltransferase II Peptide, xylosyltransferase 2 Peptide, xylt2 Peptide, XYLT2 Peptide, Xylt2 Peptide
    Hintergrund
    XYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: XT-II, XT2, xylT-II, PXYLT2

    Protein Size: 865
    Molekulargewicht
    97 kDa
    Gen-ID
    64132
    NCBI Accession
    NM_022167, NP_071450
    UniProt
    Q9H1B5
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