WW Domain Containing Transcription Regulator 1 (WWTR1) Peptid
WWTR1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle WWTR1 Produkte
- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-WWTR1 antibody (Catalog #: ARP32540_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
- Synonyme
- WWTR1 Peptide, TAZ Peptide, 2310058J06Rik Peptide, 2610021I22Rik Peptide, C78399 Peptide, Taz Peptide, WW domain containing transcription regulator 1 L homeolog Peptide, WW domain containing transcription regulator 1 Peptide, wwtr1.L Peptide, wwtr1 Peptide, WWTR1 Peptide, Wwtr1 Peptide
- Hintergrund
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TAZ (transctiptional coactivator with PDZ-binding motif), also known as WW domain containing transcription regulator 1 (WWTR1), is a member of the bicoid sub-family of homeodomain-containing transcription factors. TAZ is a 14-3-3 binding protein that co-activates Runx2-dependent gene transcription while repressing PPAR-gamma-dependent gene transcription. TAZ has been reported to be a modulator of mesenchymal stem cell differentiation. TAZ may also play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.
Alias Symbols: DKFZP586I1419, TAZ
Protein Interaction Partner: NKX2-1,PAX3,RUNX1,SLC9A3R2,TEAD3,TEAD4,YWHAE,SLC9A3R2,TEAD3,TEAD4
Protein Size: 400 - Molekulargewicht
- 44 kDa
- Gen-ID
- 25937
- NCBI Accession
- NM_015472, NP_056287
- UniProt
- Q9GZV5
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