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WAP Four-Disulfide Core Domain 1 (WFDC1) (N-Term) Peptid

WFDC1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN986193
  • Target Alle WFDC1 Produkte
    WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 7
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    WKRALPARLA EKSRAEEAGA PGGPRQPRAD RCPPPPRTLP PGACQAARCQ
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-WFDC1 Antibody(ARP57525_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))
    Synonyme
    WFDC1 Peptide, zgc:158671 Peptide, PS20 Peptide, 2310058A03Rik Peptide, ps20 Peptide, WAP four-disulfide core domain 1 Peptide, WFDC1 Peptide, wfdc1 Peptide, Wfdc1 Peptide
    Hintergrund
    This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81 % amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.

    Alias Symbols: PS20

    Protein Size: 220
    Molekulargewicht
    21 kDa
    Gen-ID
    58189
    NCBI Accession
    NM_021197, NP_067020
    UniProt
    Q9HC57
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