Thymidylate Synthetase (TYMS) Peptid
TYMS
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle TYMS Produkte
- TYMS (Thymidylate Synthetase (TYMS))
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TYMS antibody (Catalog #: ARP48543_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- TYMS (Thymidylate Synthetase (TYMS))
- Synonyme
- FN1 Peptide, ECK2823 Peptide, JW2795 Peptide, ts Peptide, Ts Peptide, HST422 Peptide, TMS Peptide, TS Peptide, thymidylate synthetase Peptide, contains intron in T4 phage Peptide, ThyE Peptide, thymidylate synthase Peptide, thymidylate synthetase L homeolog Peptide, TYMS Peptide, thyA Peptide, td Peptide, thyE Peptide, DDA3937_RS04960 Peptide, tyms.L Peptide, XBJ1_RS15770 Peptide, EAMY_RS20680 Peptide, Tyms Peptide
- Substanzklasse
- Viral Protein
- Hintergrund
-
TYMS catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-47 CR601528.1 1-47 48-1099 X02308.1 14-1065 1100-1603 BC083512.1 1067-1570
Alias Symbols: HsT422, MGC88736, TMS, TS, TSase, HST422
Protein Interaction Partner: E2F1,E2F4,TYMS
Protein Size: 313 - Molekulargewicht
- 36 kDa
- Gen-ID
- 7298
- NCBI Accession
- NM_001071, NP_001062
- UniProt
- P04818
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