This is a synthetic peptide designed for use in combination with anti-TNFRSF9 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Alias Symbols: 4-1BB, CD137, CDw137, ILA, MGC2172
Protein Interaction Partner: LRR1,TNFRSF4,TNFSF9,TRAF1,TRAF2,TRAF3,TNFRSF9,TRAF1,TRAF2,TRAF3