This is a synthetic peptide designed for use in combination with anti-TLE2 antibody (Catalog #: ARP32347_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
TLE2
(Transducin-Like Enhancer Protein 2 (TLE2))
Synonyme
TLE2 Peptide, ESG Peptide, ESG2 Peptide, GRG2 Peptide, Grg2 Peptide, mKIAA4188 Peptide, transducin like enhancer of split 2 Peptide, transducin-like enhancer of split 2 Peptide, TLE2 Peptide, Tle2 Peptide
Hintergrund
TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Alias Symbols: ESG, ESG2, FLJ41188, GRG2
Protein Interaction Partner: H3F3B,HMGB1,PRDM1,RUNX1,TLE1,UTY,HES1,PRDM1,TLE1,TLE2,UTY