This is a synthetic peptide designed for use in combination with anti-TH antibody (Catalog #: ARP30889_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The specific function of the protein remains unknown. The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: TYH, DYT14, DYT5b
Protein Interaction Partner: CAMK2G,CDK11B,CSNK2A1,MAPK1,MAPK3,MAPKAPK2,PRKACA,RPS6KA5,SNCA,YWHAB,YWHAZ,HR,MAPK1,MAPK3