Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3) Peptid
TCEB3
Reaktivität: Human
Wirt: Synthetic
BP, IHC, WB
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- Target Alle TCEB3 Produkte
- TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TCEB3 antibody (Catalog #: P100692_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))
- Synonyme
- CG6755 Peptide, Dmel\\CG6755 Peptide, Elo-A Peptide, dEloA Peptide, tceb3a Peptide, zgc:56638 Peptide, wu:fw66g10 Peptide, TCEB3 Peptide, 110kDa Peptide, AA408125 Peptide, Tceb3a Peptide, El Peptide, EloA Peptide, SIII Peptide, SIII p110 Peptide, TCEB3A Peptide, Elongin A Peptide, transcription elongation factor B polypeptide 3 Peptide, elongin A Peptide, calcium binding and coiled-coil domain 1b Peptide, elongin A S homeolog Peptide, transcription elongation factor B subunit 3 Peptide, EloA Peptide, LOC413407 Peptide, eloa Peptide, calcoco1b Peptide, ELOA Peptide, eloa.S Peptide, Eloa Peptide, TCEB3 Peptide
- Hintergrund
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Elongin A (TCEB3), which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits.This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Alias Symbols: EloA, SIII, TCEB3A, SIII p110
Protein Interaction Partner: MED21,NINL,RAP1A,REXO1,TCEB2,NINL,SOCS1,TCEB1,TCEB2
Protein Size: 772 - Molekulargewicht
- 87 kDa
- Gen-ID
- 6924
- NCBI Accession
- NM_003198, NP_003189
- UniProt
- Q14241
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