TAF6
(TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-TAF6 antibody (Catalog #: ARP38652_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF6 is one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1,the largest subunit of TFIID. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.
Protein Interaction Partner: TAF9,CIITA,GTF2E1,RELA,SH3KBP1,TAF1,TAF10,TAF11,TAF12,TAF2,TAF4,TAF5,TAF6,TAF7,TAF8,TAF9,AHR,GTF2A1,GTF2E1,RELA,SH3KBP1,TAF1,TAF12,TAF13,TAF5,TAF9,TBP,TBPL1,TP53