This is a synthetic peptide designed for use in combination with anti-Taf1c Antibody(ARP40130_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
TAF1C
(TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))
Synonyme
TAF1C Peptide, Tafi95 Peptide, mTAFI95 Peptide, MGC:39976 Peptide, SL1 Peptide, TAFI110 Peptide, TAFI95 Peptide, TATA-box binding protein associated factor, RNA polymerase I subunit C Peptide, TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa Peptide, TATA-box binding protein associated factor, RNA polymerase I, C Peptide, TATA-box binding protein associated factor, RNA polymerase 1 subunit C Peptide, TAF1C Peptide, Taf1c Peptide
Hintergrund
Taf1c is a component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Taf1c recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.