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STIP1 Homology and U-Box Containing Protein 1 (STUB1) (N-Term) Peptid

STUB1 Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN984585
  • Target Alle STUB1 Produkte
    STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-STUB1 antibody (Catalog #: ARP43058_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
    Synonyme
    CHIP Peptide, HSPABP2 Peptide, NY-CO-7 Peptide, SDCCAG7 Peptide, UBOX1 Peptide, 0610033N24Rik Peptide, 2210017D18Rik Peptide, 2310040B03Rik Peptide, AW046544 Peptide, Chip Peptide, wu:fc22f04 Peptide, zgc:56076 Peptide, STUB1 Peptide, chip Peptide, ATCHIP Peptide, CARBOXYL TERMINUS OF HSC70-INTERACTING PROTEIN Peptide, carboxyl terminus of HSC70-interacting protein Peptide, STIP1 homology and U-box containing protein 1 Peptide, STIP1 homology and U-Box containing protein 1 Peptide, STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase L homeolog Peptide, STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase Peptide, STIP1 homology and U box-containing protein 1 Peptide, carboxyl terminus of HSC70-interacting protein Peptide, STUB1 Peptide, Stub1 Peptide, stub1 Peptide, stub1.L Peptide, LOC100282870 Peptide, CHIP Peptide
    Hintergrund
    STUB1 modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. It has E3 ubiquitin-protein ligase activity and targets misfolded chaperone substrates towards proteasomal degradation. STUB1 mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation.

    Alias Symbols: CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1

    Protein Interaction Partner: HSPA8,SMAD1,SMAD4,AR,ATCAY,BAG1,BMPR1B,DNAJB1,DYX1C1,ERBB2,ESR1,GPR37,HSF1,HSP90AA1,HSPA1A,HSPA1B,HSPA4,HSPA8,KHDRBS1,MAPT,MPP1,PSMA3,PSMD4,SMAD1,SMAD2,SMAD3,SMAD4,SMURF1,TGFBR1,UBB,UBE2D1,UBE2Q1,AHR,AKT1,BAG1,CYP3A4,DNAJB1,GPR37,GUCY1A2,HSP90AA1,HSPA1A,HSPA4,HSPA8,KHDRBS1,MAP3K5,MAPT,MCF2,MPP1,PARK2,RAF1,RUNX2,STUB1,TAL1,TP53,UBA1,UBE2D1,UBE2D2,UBE2E2,XIAP

    Protein Size: 303
    Molekulargewicht
    35 kDa
    Gen-ID
    10273
    NCBI Accession
    NM_005861, NP_005852
    UniProt
    Q9UNE7
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