This is a synthetic peptide designed for use in combination with anti-STARD6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Aufreinigung
Purified
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
STARD6
(StAR-Related Lipid Transfer (START) Domain Containing 6 (STARD6))
Synonyme
1700011K09Rik Peptide, 4833424I06Rik Peptide, 4933429L05Rik Peptide, AI644424 Peptide, StAR related lipid transfer domain containing 6 Peptide, StAR-related lipid transfer (START) domain containing 6 Peptide, STARD6 Peptide, Stard6 Peptide
Hintergrund
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins and by liver X receptors. Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein. STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD6.