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Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5) Peptid

SLC26A5 Reaktivität: Human Wirt: Synthetic BP, IHC, WB
Produktnummer ABIN983934
  • Target Alle SLC26A5 Produkte
    SLC26A5 (Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5))
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-SLC26A5 antibody (Catalog #: ARP44176_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SLC26A5 (Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5))
    Synonyme
    pres Peptide, fb73d12 Peptide, fb74g12 Peptide, wu:fb73d12 Peptide, wu:fb74g12 Peptide, DFNB61 Peptide, PRES Peptide, Pres Peptide, prestin Peptide, solute carrier family 26 (anion exchanger), member 5 Peptide, solute carrier family 26 member 5 Peptide, solute carrier family 26, member 5 Peptide, slc26a5 Peptide, SLC26A5 Peptide, Slc26a5 Peptide
    Hintergrund
    SLC26A5 is a member of the SLC26A/SulP transporter family. SLC26A5 is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in its gene have been associated with non-syndromic hearing loss.This gene is a member of the SLC26A/SulP transporter family. It encodes a protein that is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in this gene have been associated with non-syndromic hearing loss. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Alias Symbols: DFNB61, MGC118886, MGC118887, MGC118888, MGC118889, PRES

    Protein Size: 744
    Molekulargewicht
    81 kDa
    Gen-ID
    375611
    NCBI Accession
    NM_198999, NP_945350
    UniProt
    P58743
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