SIN3 Transcription Regulator Homolog B (SIN3B) (Middle Region) Peptid
SIN3B
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle SIN3B Produkte
- SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SIN3B antibody (Catalog #: ARP50590_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
- Synonyme
- fj63d08 Peptide, si:dkey-6n6.6 Peptide, wu:fj63d08 Peptide, 2810430C10Rik Peptide, SIN3 transcription regulator family member B Peptide, SIN3 transcription regulator family member B S homeolog Peptide, transcriptional regulator, SIN3B (yeast) Peptide, sin3b Peptide, SIN3B Peptide, sin3b.S Peptide, Sin3b Peptide
- Hintergrund
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SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also, it interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. The gene is also able to form a complex with FOXK1 which represses transcription
Alias Symbols: KIAA0700
Protein Interaction Partner: HDAC1,HDAC9,IKZF1,IKZF4,MAD1L1,MXD1,MXI1,REST,SETDB1,ZBTB16,HCFC1,HDAC1,HDAC9,IKZF1,IKZF2,IKZF3,IKZF4,MECP2,RNF220,SAP30,SETDB1,SUDS3,WHSC1,ZBTB16
Protein Size: 1162 - Molekulargewicht
- 133 kDa
- Gen-ID
- 23309
- NCBI Accession
- NM_015260, NP_056075
- UniProt
- O75182
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