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Short Stature Homeobox 2 (SHOX2) (N-Term) Peptid

SHOX2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN983719
  • Target Alle SHOX2 Produkte
    SHOX2 (Short Stature Homeobox 2 (SHOX2))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-SHOX2 antibody (Catalog #: ARP33285_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SHOX2 (Short Stature Homeobox 2 (SHOX2))
    Synonyme
    SHOX2 Peptide, og12 Peptide, shot Peptide, og12x Peptide, ogi2x Peptide, OG12 Peptide, OG12X Peptide, SHOT Peptide, 6330543G17Rik Peptide, Og12x Peptide, Prx3 Peptide, zgc:65884 Peptide, zgc:77344 Peptide, short stature homeobox 2 Peptide, SHOX2 Peptide, shox2 Peptide, Shox2 Peptide
    Hintergrund
    SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.

    Alias Symbols: OG12, OG12X, OGI2X, SHOT

    Protein Size: 331
    Molekulargewicht
    35 kDa
    Gen-ID
    6474
    NCBI Accession
    NM_006884, NP_006875
    UniProt
    O60902
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