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15 KDa Selenoprotein (SEP15) Peptid

SEP15 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN983549
  • Target Alle Sep 15 (SEP15) Produkte
    Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-SEP15 antibody (Catalog #: ARP48247_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))
    Synonyme
    9430015P09Rik Peptide, cb29 Peptide, zgc:86882 Peptide, BcDNA:SD16138 Peptide, Dmel\\CG7484 Peptide, Prise 8 Peptide, Sep15 Peptide, selenoprotein F Peptide, CG7484 gene product from transcript CG7484-RB Peptide, SELENOF Peptide, Selenof Peptide, selenof Peptide, CG7484 Peptide
    Hintergrund
    SEP15 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. The gene that encodes the protein is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Alias Symbols: -

    Protein Interaction Partner: UGGT1,UGGT2

    Protein Size: 165
    Molekulargewicht
    15 kDa
    Gen-ID
    9403
    NCBI Accession
    NM_004261, NP_004252
    UniProt
    O60613
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