seryl-tRNA Synthetase 2, Mitochondrial (SARS2) (N-Term) Peptid
SARS2
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle SARS2 Produkte
- SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- EEKAAVTEAV RALLANQDSG EVQQDPKYQG LRARGREIRK ELVHLYPREA
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SARS2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))
- Synonyme
- 2410015F05Rik Peptide, D7Ertd353e Peptide, SerRS Peptide, SerRSmt Peptide, SARS Peptide, SARSM Peptide, SERS Peptide, SYS Peptide, mtSerRS Peptide, seryl-aminoacyl-tRNA synthetase 2 Peptide, seryl-tRNA synthetase 2, mitochondrial Peptide, Sars2 Peptide, SARS2 Peptide
- Hintergrund
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This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease.
Alias Symbols: FLJ20450, SARS, SARSM, SERS, SYS, SerRSmt, mtSerRS, SerRS
Protein Interaction Partner: CASP3,EEF1A1,DMWD,PUF60,USP44
Protein Size: 518 - Molekulargewicht
- 57 kDa
- Gen-ID
- 54938
- NCBI Accession
- NM_017827, NP_060297
- UniProt
- Q9NP81
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