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RFT1 Homolog (RFT1) Peptid

RFT1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN982882
  • Target Alle RFT1 Produkte
    RFT1 (RFT1 Homolog (RFT1))
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-RFT1 antibody (Catalog #: ARP50203_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RFT1 (RFT1 Homolog (RFT1))
    Synonyme
    GB14370 Peptide, CDG1N Peptide, D930025H04 Peptide, RGD1562654 Peptide, protein RFT1 homolog Peptide, RFT1 homolog Peptide, LOC412489 Peptide, LOC100453537 Peptide, RFT1 Peptide, rft1 Peptide, LOC100633251 Peptide, LOC100651701 Peptide, Rft1 Peptide
    Hintergrund
    N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a??Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation.N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a Man(5)GlcNAc(2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man(5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation (Helenius et al., 2002 [PubMed 11807558]).[supplied by OMIM].

    Alias Symbols: CDG1N

    Protein Size: 541
    Molekulargewicht
    60 kDa
    Gen-ID
    91869
    NCBI Accession
    NM_052859, NP_443091
    UniProt
    Q96AA3
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