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Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN) (Middle Region) Peptid

PTPRN Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN982460
  • Target Alle PTPRN Produkte
    PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    EVQQVPSPVS SEPPKAARPP VTPVLLEKKS PLGQSQPTVA GQPSARPAAE
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PTPRN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
    Synonyme
    IA-2 Peptide, IA-2/PTP Peptide, IA2 Peptide, ICA512 Peptide, R-PTP-N Peptide, mIA-A Peptide, mKIAA4064 Peptide, Ia-2 Peptide, fc43c04 Peptide, ptprn Peptide, wu:fc43c04 Peptide, ia-2 Peptide, ia2 Peptide, ica512 Peptide, r-ptp-n Peptide, protein tyrosine phosphatase, receptor type N Peptide, protein tyrosine phosphatase, receptor type, N Peptide, protein tyrosine phosphatase, receptor type, Na Peptide, protein tyrosine phosphatase, receptor type N L homeolog Peptide, PTPRN Peptide, Ptprn Peptide, ptprna Peptide, ptprn.L Peptide
    Hintergrund
    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.

    Alias Symbols: IA2, IA-2, ICA512, R-PTP-N, IA-2/PTP

    Protein Size: 889
    Molekulargewicht
    66 kDa
    Gen-ID
    5798
    NCBI Accession
    NM_001199763, NP_001186692
    UniProt
    Q16849
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