This is a synthetic peptide designed for use in combination with anti-PPHLN1 Antibody(ARP57819_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: HSPC206, HSPC232, MGC48786
Protein Interaction Partner: CASP5,PPHLN1,PPL,TGM2,TOMM20,VIM,CASP5,PPL,TOMM20