Peroxisome Proliferator-Activated Receptor gamma (PPARG) (N-Term) Peptid
PPARG
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle PPARG Produkte
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PPARG antibody (Catalog #: ARP32879_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
- Synonyme
- PPAR gamma Peptide, PPARg2 Peptide, PPARG Peptide, Nr1c3 Peptide, PPAR-gamma Peptide, PPAR-gamma2 Peptide, PPARgamma Peptide, PPARgamma2 Peptide, NR1C3 Peptide, CIMT1 Peptide, GLM1 Peptide, PPARG1 Peptide, PPARG2 Peptide, xPPAR-gamma Peptide, PPAR-GAMMA Peptide, PPARGAMMA Peptide, peroxisome proliferator-activated receptor gamma Peptide, peroxisome proliferator activated receptor gamma Peptide, peroxisome proliferator activated receptor gamma L homeolog Peptide, PPARG Peptide, Pparg Peptide, pparg.L Peptide
- Hintergrund
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PPARG is a receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. PPARG is the key regulator of adipocyte differentiation and glucose homeostasis.This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
Alias Symbols: NR1C3, PPARG1, PPARG2, GLM1, CIMT1, PPARgamma
Protein Interaction Partner: CEP350,BRD8,CNOT1,COPS5,DNTTIP2,EDF1,FABP1,FOXO1,GADD45B,GADD45G,HDAC3,HMGA1,KIF1A,MAPK1,MAPK8,MED1,MED24,NCOA1,NCOA2,NCOA3,NCOA4,NCOA6,NCOR1,NCOR2,NFE2L2,NR0B1,NR0B2,NRIP1,PPARG,PPARGC1A,PRIC285,RANBP9,RXRA,RXRB,RXRG,SMARCD3,SYT1,BCAS2,CREBBP,DNTTIP2,EDF1,EP300,FABP1,GADD45G,Gadd45b,HDAC3,HDAC4,MED1,MED24,MPG,NCOA2,NCOA3,NCOA4,NFE2L2,NR0B2,NRIP1,POU1F1,PPARGC1A,PRMT2,RB1,RXRA,SVIL
Protein Size: 505 - Molekulargewicht
- 57 kDa
- Gen-ID
- 5468
- NCBI Accession
- NM_015869, NP_056953
- UniProt
- P37231
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