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Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (Middle Region) Peptid

PNRC2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN981927
  • Target Alle PNRC2 Produkte
    PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    NQSWNSSLSG PRLLFKSQAN QNYAGAKFSE PPSPSVLPKP PSHWVPVSFN
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PNRC2 Antibody(ARP57028_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))
    Synonyme
    0610011E17Rik Peptide, D4Bwg0593e Peptide, wu:cegs2777 Peptide, wu:fb51a04 Peptide, wu:fb81a06 Peptide, wu:fd19g06 Peptide, proline rich nuclear receptor coactivator 2 Peptide, proline-rich nuclear receptor coactivator 2 Peptide, PNRC2 Peptide, Pnrc2 Peptide, pnrc2 Peptide
    Hintergrund
    PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery.PNRC2 may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. PNRC2 is required for UPF1/RENT1 localization to the P-body. PNRC2 also acts as a nuclear receptor coactivator. PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure.

    Alias Symbols: FLJ20312, MGC99541

    Protein Interaction Partner: AR,ESR1,ESR2,ESRRA,ESRRG,HNF4A,HNF4G,NR5A1,NR5A2,RARA,RARG,RORA,RORB,ZBTB16

    Protein Size: 139
    Molekulargewicht
    15 kDa
    Gen-ID
    55629
    NCBI Accession
    NM_017761, NP_060231
    UniProt
    Q9NPJ4
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