This is a synthetic peptide designed for use in combination with anti-PNRC2 Antibody(ARP57028_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery.PNRC2 may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. PNRC2 is required for UPF1/RENT1 localization to the P-body. PNRC2 also acts as a nuclear receptor coactivator. PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure.
Alias Symbols: FLJ20312, MGC99541
Protein Interaction Partner: AR,ESR1,ESR2,ESRRA,ESRRG,HNF4A,HNF4G,NR5A1,NR5A2,RARA,RARG,RORA,RORB,ZBTB16