Protein Inhibitor of Activated STAT, 1 (PIAS1) (N-Term) Peptid

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Proteinname
  • 2900068C24Rik
  • Ddxbp1
  • GBP
  • DDXBP1
  • GU/RH-II
  • ZMIZ3
  • ddxbp1
  • gbp
  • pias
  • pias1-A
  • xPAIS1
  • xPIAS1
  • zmiz3
  • protein inhibitor of activated STAT 1
  • protein inhibitor of activated STAT, 1
  • protein inhibitor of activated STAT, 1a
  • protein inhibitor of activated STAT 1 L homeolog
  • PIAS1
  • Pias1
  • pias1a
  • pias1.L
Protein Region
N-Term
Spezies
Human
4
1
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Geblockter Antikörper anti-PIAS1 Antikörper (Protein Inhibitor of Activated STAT, 1) (N-Term) (ABIN2780997)
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-PIAS1 antibody (Catalog #: ARP39231_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Hintergrund PIAS1 is a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: DDXBP1, GBP, GU/RH-II, MGC141878, MGC141879, ZMIZ3

Protein Interaction Partner: CEBPA,CEBPE,CASP8,CSRP2,ESR1,HTNVsSgp1,SUMO1,TP53,UBE2I,AR,AXIN1,CASP8,CEBPA,CEBPE,CHUK,CREBBP,CSRP2,DCLRE1A,DDX21,DNM1,DNMT3A,ELK3,ESR1,ESR2,GATA4,GRM8,JUN,MBD1,MDM2,MSX1,NIN,NR2F2,NR3C2,NR5A1,PGR,PIAS1,PIAS2,PIAS4,PRPF40A,PTK2,PTPN1,RELA,SATB2,SERBP1,SKIL,SMAD1,SMAD4,SMAD7,SNIP1,SP3,STAT1,SUFU,SUMO1,TBP,TP53,TP73,UBE2I,ZNF76,AKT1,AR,CSRP2,DNMT3A,MX1,SIAH1,SIAH2,SP3,STAB2,STAT1,SUMO1,SUMO2,TP53,UBE2I,ZMIZ2

Protein Size: 651
Molekulargewicht 72 kDa
Gen-ID 8554
NCBI Accession NM_016166, NP_057250
UniProt O75925
Applikationshinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.