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6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (C-Term) Peptid

PFKFB1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN981614
  • Target Alle PFKFB1 Produkte
    PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    EEMTYEEIQE HYPEEFALRD QDKYRYRYPK GESYEDLVQR LEPVIMELER
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PFKFB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
    Synonyme
    zgc:55328 Peptide, wu:fi11h10 Peptide, PFKFB1 Peptide, F6PK Peptide, HL2K Peptide, PFRX Peptide, Pfkfb01 Peptide, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Peptide, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog Peptide, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 Peptide, pfkfb1 Peptide, PFKFB1 Peptide, pfkfb1.S Peptide, LOC100475853 Peptide, Pfkfb1 Peptide
    Hintergrund
    This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.

    Alias Symbols: F6PK, HL2K, MGC116715, MGC116717, PFRX

    Protein Size: 471
    Molekulargewicht
    52 kDa
    Gen-ID
    5207
    NCBI Accession
    NM_002625, NP_002616
    UniProt
    P16118
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